Abstract: The injection water for the desert oil field is clean water, and the water quality at the wellhead can't meet the water quality standard. Through the quality tracking detection of injection water from Xinjiang oilfield——Shinan 4 oilfield and Mobei oilfield respectively, a novel fungicide HT/SJJ-01 was researched and developed. The fungicide makes use of the synergistic effect of multi-component pharmaceutical synergies, so that its performance has been significantly improved. The injection water of the oil transfer station in Mobei oilfield had been tested for one month. The results showed that the water quality was stable during the whole test process, the water quality after treated is more better than that of before the pilot test and does not appear the second pollution phenomenon, which can ensure that the bacteria content of injection wells meets the requirements of Injection Water Quality Standard of Mobei Oilfield