Abstract: According to EIA report requirements, the industrial and overhaul waste water of Luojiazhai and Gunziping shall be reinjected into ground via reinjection well after treatment. The distance between natural gas treatment plant of Luojiazhai or Gunziping gas field to reinjection well is far away, so the reliability & feasibility of reinjection wellhead data transmission design is very critical for real-time monitoring of pressure, temperature and flow in reinjection well & pipeline as well as alarming on time when accident happens during reinjection. From the point of design, this paper specified the feasible scenarios of reinjection wellhead data transmission. GPRS wireless data transmission should be the best scenario for this project through comparisons, which might provide some reference for other similar data transmission projects.