Abstract: Shanan oil field has the geological characteristics of high temperature, high salinity, low permeability and water sensitivity. In recent years, the production situation is more serious with the degree of water drive decreasing year by year. To improve this situation, the pilot test of gel polymer profile control and flooding technology was carried out in Shaqiu 5 wellblock of Shanan oil field. At first, the water well was made a full profile control with composite organic gel particles profile control agent with a tolerance of temperature and salt, and then oil displacement agent of 0.3% was injected for displacing oil. The Application result showed that this technology has the good effect in enhancing production of oil and precipitation with efficiency of 85.7% for 12 wells among tested 14 well times, and total oil increment was 3 069.6 t. Compared with non experimental area, the level of oil decline in experimental area decreased significantly. The way of profile control and flooding played an obvious role in controlling production of oil.