Abstract: As the toxicity of H₂S in natural gas, desulfurization is necessary before the use of natural gas. Because of the huge shear stress of rotating packed bed, it will greatly improve the transfer rate coefficient and increase the production capacity of the device. The device size is much smaller than conventional tower. High gravity technology combined with redox has good application value in the field of natural gas desulfurization. Therefore establishing a practical and reliable mass transfer coefficient model is important for desulfurization of high gravity technology. The data in a pilot plant by chelated iron desulfurization redox has been got with the mixture of methane and hydrogen sulfide simulations of natural gas. According to the data and characteristics of gas-liquid contact in rotating packed bed, the effect of gas flow rate, liquid flow rate and rotor speed on volumetric mass transfer coefficient were studied. Using Matlab to fit analysis related data, the empirical models of mass transfer coefficient were obtained. Finally, comparing the mass transfer coefficient empirical model and experimental data, the analysis and comparison results showed that the model has high degree of agreement with the experimental data, and the average deviation is only 0.12%. The model can be extrapolated to other similar device which has similar volume with the high gravity device, but the gas flow should be in the range of 1-10 m³/h, the liquid flow of 0.1-1 m³/h, and the speed of 100-1 500 r/min.