Abstract: A clean supramolecular polymer CO₂ foam fracturing fluid with high temperature resistance was compounded with a polymer synthesized by several polymerization monomers and introducing specific functional groups, related additives and CO₂. The system was evaluated through the performance evaluation method of foam fracturing fluid: the temperature resistance has reached 140 ℃, with the advantages of high foam quality, long half-life, strong temperature and shear resistance, good performance of sand carrying, etc., and fracturing fluid gel would be broken completely, which has low surface tension (less than 24 mN·m^-1) and very low residue (less than 1 mg·L^-1). The system not only solved the high residue content problem of conventional guar gum-CO₂ foam fracturing fluid, but also overcame the shortcomings of poor compatibility with CO₂ and low resistance to high temperature and shearing of VES-CO₂ foam fracturing fluid. The system has successful implementation and good effect of increasing production in a shale gas well of Yanchang oil field, and it has great advantages in efficient development and reservoir protection of special oil and gas reservoir with low permeability, low pressure, easy water lock and strong water sensitivity.