Abstract: The application of RSS-2 catalyst in aviation kerosene hydrotreating unit in refinery of PetroChina Lanzhou Petrochemical Company was introduced. The results showed that the sulfur mass fraction of refined aviation kerosene was reduced from 138 μg/g to 3 μg/g and the desulfurization rate reached 97.83%, the basic nitrogen mass fraction of refined aviation kerosene was reduced from 2.71 μg/g to 0.12 μg/g and the basic nitrogen removal efficiency was 95.57% at the process operation condition of feed rate 71.4 t/h, reactor inlet temperature 278.5 ℃, reaction pressure 3.72 MPa, volume space velocity 3.72 h^-1, and hydrogen-oil ratio 181. Using straight run kerosene as raw material, refined aviation kerosene met the quality specification of No. 3 jet fuel. In order to meet the production requirement of low freezing point diesel, atmospheric cut 2 diesel was blended with straight run kerosene. When the blending ratio was increased from 25% to 50%, the sulfur mass fraction in mixed feed was reduced to below 20 μg/g, which could meet the blending requirement of low freezing point diesel specified by the national standard Ⅳ. The results showed that the RSS-2 catalyst has good hydrodesulfurization and hydrodenitrogenation effect.