Abstract: In order to save the energy and reduce the emission of CO₂ in the tail gas from natural gas purification plant, the absorption performance of MEA and compound amine to CO₂ were verified by laboratory experiments, simulation experiments and side line experiments respectively. Combined with the experimental study, field test and evaluation, the CO₂ recovery process suitable for the tail gas condition of Puguang Natural Gas Purification Plant was developed, which can provide technical supports for achieving low carbon production and CO₂ emission reduction in natural gas purification plants.