Abstract: A stirred-kettle hydrate production experimental device was used to study effects of dynamic accelerator SDS (twelve sodium dodecyl sulfate) and thermodynamic accelerator THF (tetrahydrofuran) on CO₂ captured from simulated flue gas by hydrate based gas separation (HBGS). Mixed gas contained CO₂ with a mole fraction of 25% and N₂ with a mole fraction of 75% was used to simulate flue gas. The effects of different concentrations of SDS and THF on the separation effect were studied. On this basis, the effects of different initial pressures and different reaction temperatures on the separation efficiency were studied. The results showed that both SDS and THF could increase the CO₂ recovery, but simultaneously reduce the separation factor. When the temperature was 3.5 ℃ and the initial pressure was 9.2 MPa, adding 0.01 wt% SDS, the CO₂ recovery increased by 4.3% and the separation factor decreased by 44.8% compared with pure water. When the temperature was 6.5 ℃ and the initial pressure was 3.7 MPa, adding 0.5 mol% THF, the CO₂ recovery increased by 30.4% and the separation factor decreased by 72.8% compared with pure water. Under experimental conditions, more appropriate concentration of SDS and THF are 0.01 wt%-0.05 wt% and 0.5 mol%-2 mol%, respectively. The initial pressure increaseing can effectively shorten the hydration reaction induction time, increase the gas storage density, CO₂ recovery and separation factor. Reducing the temperature can effectively improve the separation efficiency.