Abstract: There are 25 production wells in DINA-2 high temperature and high pressure condensate gas reservoir of Tarim oilfield, and the problems of scale formation and blockage in the wellbore are occured among 19 wells. The produced water mainly are condensate water in DINA-2 gas field, there has no systematic research result on scale formation of condensate water at home and abroad, and the existing descaling method by using descaling agent shows slow effect and high cost. Then the study on the distribution law of scale formation, scale composition, the cause of scale formation and descaling measure in the wellbore of high temperature and high pressure condensate gas reservoir is needed. In this paper, according to the precise subsection sampling, laboratory test, the analysis of scale formation and the study of scale removal measures, it is clear that scaling is mainly concentrated in the local location of wellbore diameter reduction. The reasons of condensate water scale formation are the transformation of part confined water into mobile formation water and the dissolution of partial backfill in the production process, which provides mineral ions. The eddy action at the diameter reducing position of wellbore causes the change of flow field, flow state and phase state, leading to the aggregation and re-evaporation of liquid, resulting in scale formation (salting out). The soil acidification can effectively remove wellbore scaling and plugging. In this paper, the study of condensate water scaling in wellbore of condensate gas reservoir is developed for the first time, the scale removal measures are proposed, and the mechanism of condensate water scaling is provided, which provides the theoretical basis for scale formation of condensate water in wellbore, and effectively restore the normal production of gas wells.