Abstract: An analytical method for simultaneous determination of heat stable salts in alkanolamine solutions represented by N-methyldiethanolamine was established by isocratic elution ion chromatography. In this method, the sample of alkanolamine solution diluted with deionized water and filtered by 0.45 μm membrane was separated and detected under the optimized ion chromatographic elution conditions (2 mmol/L Na₂CO₃ + 8 mmol/L NaHCO₃), and quantified by external standard method, thus realizing the simultaneous determination of seven heat stable salt anions such as formate, chloride, nitrate, sulfate, thiocyanate, oxalate and thiosulfate. Methodological results showed that the linearity of each ion was good in the concentration range of 5-80 μg/mL, the correlation coefficient was greater than 0.999 5, the precision(RSD) was less than 5%, and the recovery rate of three concentration levels was between 85%-98%. The method has been successfully applied to the determination of seven heat stable salt anions in five samples. The analytical method for determination of seven kinds of heat stable salts in alkanolamine solution established in this work is simple in pretreatment, good in repeatability, accurate in results, reliable and practical.